Increasing / optimizing the antidepressant dose

If the patient is not yet responding, and if the maximum is not yet reached, consider increasing / optimizing the dosage, up to the recommended maximum dosage.

Do not increase/maximize the antidepressant dose if:
  • There are significant side effects or drug allergies
  • Significant risk of drug interactions

Note: Lower doses or less frequent dosage increase may be better for anxious or medically compromised patients.